Hauj lwm lawm
Chemical Structure: Cilofexor
CAS Nr.: 1418274-28-8
Cilofexor(GS-9674; GS9674; PX-104)
Catalog No.: YL-588Tsuas yog siv rau Lab.
Cilofexor (GS-9674, GS9674, PX{2}}) yog cov tshiab tshwj xeeb, uas tsis yog-steroidal farnesoid X receptor (FXR) agonist uas txo lub siab fibrosis thiab ameliorates portal hypertension hauv nas NASH qauv.
Kev ua lom lom
Cilofexor (GS-9674, GS9674, PX-104) yog ib qho tshiab tshwj xeeb, uas tsis yog-steroidal farnesoid X receptor (FXR) agonist uas txo lub siab fibrosis thiab ameliorates portal hypertension hauv nas NASH qauv.
Steatohepatitis
Phase 2 Clinical
Physicochemical Properties
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M.Wt |
386.85 |
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Formula |
C28H22Cl3N3O5 |
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CAS Nr. |
1418274-28-8 |
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Cia |
Hmoov hmoov -20 degree 12 Lub Hlis; 4 degree 6 hli |
Hauv Solvent -20 degree 6 Lub Hlis |
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Solubility |
10 mM hauv DMSO |
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Tshuaj npe |
Cilofexor; Cilofexor (GS{0}}); 2-(3-(2-chloro-4-((5-}cyclopropyl-3-(2 ,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid |
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Cov ntaub ntawv
1. Gege C, et al. Curr Top Med Chem. 2014; 14(19):{4}}.
URK-V588_COAURK-V588_DataSheetURK-V588_HNMR ReportURK-V588_LCMS ReportURK-V588_SDS
Nco tseg: Tag nrho cov khoom ntawm Ureiko tsuas yog siv rau kev tshawb fawb tshawb fawb lossis kev tshaj tawm daim ntawv pov thawj tshuaj, thiab peb tsis muab cov khoom thiab cov kev pabcuam rau kev siv tus kheej!
Cim npe nrov: cilofexor cas no.: 1418274-28-8
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