Hauj lwm lawm
Chemical Structure: SR-11302
CAS Nr.: 160162-42-5
SR -11302(SIB 11302)
Catalog No.Qauv: URK-V2319Tsuas yog siv rau Lab.
SR-11302( SR11302) yog ib qho tshwj xeeb, me me molecule inhibitor ntawm activator protein-1 (AP-1), inhibits AP-1 kev ua si yam tsis tau ua kom muaj kev hloov pauv ntawm RARE.
Kev ua lom lom
SR-11302( SR11302) yog ib qho tshwj xeeb, me me molecule inhibitor ntawm activator protein-1 (AP-1), inhibits AP-1 kev ua si yam tsis tau ua kom muaj kev hloov pauv ntawm RARE.
SR-11302 inhibits qog qog nyob rau hauv AP-1-luciferase transgenic nas, inhibits papilloma tsim thaum lub sij hawm ntawm kev loj hlob qog. SR-11302 blocks TPA-induced AP-1 transactivation hauv AP-1-luciferase transgenic nas.
SR-11302 txo VEGF kev txhawb nqa kev ua haujlwm thiab txo qis c-Fos qhia thiab tso tawm.
SR-11302 txo cov kab mob metastatic nyob rau hauv 4D qauv ntawm mob ntsws cancer.
Physicochemical Properties
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M.Wt |
376.540 |
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Formula |
C26H32O2 |
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CAS Nr. |
160162-42-5 |
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Cia |
Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos |
Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis |
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Solubility |
10 mM hauv DMSO |
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Tshuaj npe |
3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4 ,6,{11}}tetraenoic acid |
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Cov ntaub ntawv
1. Maron BA, et al. Kev ncig. 2014 Jul 8;130(2):168-79.
2. Huang C, et al. Proc Natl Acad Sci US A. 1997 Tsib Hlis 27; 94(11):5826-30.
3. Li JJ, et al. Cancer Res. 1997 Aug 15;57(16):3569-76.
4. Catar R, et al. Raum Int. 2013 Dec; 84(6):{4}}.
URK-V2319_COAURK-V2319_SDSURK-V2319_TDSNco tseg: Tag nrho cov khoom ntawm Ureiko tsuas yog siv rau kev tshawb fawb tshawb fawb lossis kev tshaj tawm daim ntawv pov thawj tshuaj, thiab peb tsis muab cov khoom thiab cov kev pabcuam rau kev siv tus kheej!
Cim npe nrov: sr 11302 cas no.:160162-42-5
Xa kev nug
Koj Tseem Yuav Zoo Li
