Hauj lwm lawm
Chemical Structure: PF-04745637
CAS Nr.: 1917294-46-2
PF-04745637(PIB 04745637, PF04745637)
Catalog No.Qauv: URK-V655Tsuas yog siv rau Lab.
PF-04745637 yog lub zog thiab xaiv TRPA1 antagonist nrog IC50 ntawm 17 nM rau tib neeg TRPA1
Kev ua lom lom
PF-04745637 yog lub zog thiab xaiv TRPA1 antagonist nrog IC50 ntawm 17 nM rau tib neeg TRPA1
Physicochemical Properties
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M.Wt |
509.00 |
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Formula |
C27H32ClF3N2O2 |
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CAS Nr. |
1917294-46-2 |
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Cia |
Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos |
Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis |
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Solubility |
10 mM hauv DMSO |
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Tshuaj npe |
1-(4-chlorophenyl)-N-(2-(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)-3- phenylpropyl)cyclopentane-1-carboxamide |
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Cov ntaub ntawv
Laurie B. Schenkel, et al. Kev tshawb pom ntawm cov muaj zog series ntawm carboxamide TRPA1 antagonists. J. Med. Chem. Xyoo 2016, 59, 6, 2794-2809.
URK-V655_COAURK-V655_SDSURK-V655_TDS
Nco tseg: Tag nrho cov khoom ntawm Ureiko tsuas yog siv rau kev tshawb fawb tshawb fawb lossis kev tshaj tawm daim ntawv pov thawj tshuaj, thiab peb tsis muab cov khoom thiab cov kev pabcuam rau kev siv tus kheej!
Cim npe nrov: pf-04745637 cas no.:1917294-46-2
Xa kev nug
Koj Tseem Yuav Zoo Li
