INCB057643 CAS Nr.: 1820889-23-3
Qauv: INCB 057643
CAS Nr.: 1820889-23-3
Purity: >98 feem pua (HPLC)
Hauj lwm lawm
Qauv: INCB 057643
CAS Nr.: 1820889-23-3
Purity: >98 feem pua (HPLC)
ib 057643(INCB057643, IB-057643)
Catalog No.Qauv: URK-V594Tsuas yog siv rau Lab.
INCB 057643 yog ib qho kev xaiv tshiab, muaj zog hais lus bioavailable BET inhibitor.
Kev ua lom lom
INCB 057643 yog ib qho kev xaiv tshiab, muaj peev xwm hais lus bioavailable BET inhibitor, khi rau cov motifs uas paub txog acetylated lysines hauv cheeb tsam BRD ntawm BET protein, yog li tiv thaiv kev cuam tshuam ntawm BET protein nrog histone acetylated lysines.
Cov qog nqaij hlav
Phase 2 Clinical
Physicochemical Properties
|
M.Wt |
415.464 |
|
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Formula |
C20H21N3O5S |
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CAS Nr. |
1820889-23-3 |
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|
Cia |
Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos |
Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis |
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Solubility |
10 mM hauv DMSO |
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Tshuaj npe |
2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2 ,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-benzo[b][1,4]oxazin-3(4H)- ib |
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Cov ntaub ntawv
1. Wilson AJ, et al. Gynecol Oncol. 2018 Mar 20. pii: S0090-8258(18)30229-4.
URK-V594_COAURK-V594_SDSURK-V594_TDS
Nco tseg: Tag nrho cov khoom ntawm Ureiko tsuas yog siv rau kev tshawb fawb tshawb fawb lossis kev tshaj tawm daim ntawv pov thawj tshuaj, thiab peb tsis muab cov khoom thiab cov kev pabcuam rau kev siv tus kheej!
Cim npe nrov: incb057643 cas no.: 1820889-23-3
Xa kev nug
Koj Tseem Yuav Zoo Li
