RET Agonist BT44 CAS No.: 924759-42-2
Chemical Structure: RET Agonist BT44
CAS Nr.: 924759-42-2
Hauj lwm lawm
Chemical Structure: RET Agonist BT44
CAS Nr.: 924759-42-2
RET Agonist BT44
Catalog No.: URK-V2368 Tsuas yog Siv Rau Lab.
Novel thiab tshwj xeeb RET agonist BT-44 yog ib qho me me rau kev kho mob ntawm kev sim neuropathies, txhawb RET phosphorylation thiab xaiv activates downstream cascades hauv cov hlwb qhia GFL receptors.
Kev ua lom lom
Novel thiab tshwj xeeb RET agonist BT-44 yog ib qho me me rau kev kho mob ntawm kev sim neuropathies,
BT-44 xaiv qhib RET thiab intracellular pro-survival AKT thiab MAPK taw qhia txoj hauv kev hauv cov hlwb tsis txawj tuag.
BT-44 kuj tau tiv thaiv kab lis kev cai qus-hom dopamine neurons los ntawm MPP ntxiv rau -induced toxicity
Physicochemical Properties
|
M.Wt |
577.595 |
|
|
Formula |
C28H27F4N3O4S |
|
|
CAS Nr. |
924759-42-2 |
|
|
Cia |
Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos |
Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis |
|
Solubility |
10 mM hauv DMSO |
|
|
Tshuaj npe |
|
|
Cov ntaub ntawv
1, Phau ntawv Journal of Parkinson's Disease, vol. 11, nr. 3, pp. 1023-1046, 2021
2, Viisanen H, et al.Mol Mob.2020 Lub Ib Hlis-Lub Kaum Ob Hlis 16: 1744806920950866.
3, Renko JM, et al.J Parkinsons Dis.2021;11(3):1023-1046.
Nco tseg: Tag nrho cov khoom ntawm Ureiko tsuas yog siv rau kev tshawb fawb tshawb fawb lossis kev tshaj tawm daim ntawv pov thawj tshuaj, thiab peb tsis muab cov khoom thiab cov kev pabcuam rau kev siv tus kheej!
Cim npe nrov: ret agonist bt44 cas no.: 924759-42-2, China ret agonist bt44 cas no.: 924759-42-2
Xa kev nug
Koj Tseem Yuav Zoo Li
