MK256 CAS Nr.: 2271348-04-8
M.Wt: 317.142
Cov roj formula: C14H9BrN2O2
CAS Nr.: 2271348-04-8
Hauj lwm lawm
Chemical Structure: MK256
CAS Nr.: 2271348-04-8
TIAB SA 256
Catalog No.Qauv: URK-V2376Tsuas yog siv rau Lab.
MK256 yog ib qho tshiab me me molecules CDK8 inhibitor nrog lub zog tiv thaiv kev ua haujlwm hauv AML los ntawm kev txo qis ntawm txoj hauv kev STAT
Kev ua lom lom
MK256 yog ib qho tshiab me me molecules CDK8 inhibitor nrog lub zog tiv thaiv kev ua haujlwm hauv AML los ntawm kev txo qis ntawm txoj hauv kev STAT.
MK256, lub zog, xaiv, thiab hais lus muaj CDK8 inhibitor tau tsim los rau lub hom phiaj AML.
MK256 inhibite proliferation ntawm AML cell kab.
MK256 tsis tsuas yog txo qis phosphorylated STAT1 (S727) thiab STAT5 (S726), tab sis kuj txo qis mRNA kab lus ntawm MCL-1 thiab CCL2 hauv AML cell kab.
Physicochemical Properties
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M.Wt |
317.142 |
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Formula |
C14H9BrN2O2 |
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CAS Nr. |
2271348-04-8 |
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Cia |
Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos |
Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis |
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Solubility |
10 mM hauv DMSO |
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Tshuaj npe |
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Cov ntaub ntawv
[1] Jen-Chieh Lee, Shu Liu, et al. Oncotarget. 2022 Nov 2; 13:1217-1236.
URK-V2376_COAURK-V2376_SDSURK-V2376_TDS
Nco tseg: Tag nrho cov khoom ntawm Ureiko tsuas yog siv rau kev tshawb fawb tshawb fawb lossis kev tshaj tawm daim ntawv pov thawj tshuaj, thiab peb tsis muab cov khoom thiab cov kev pabcuam rau kev siv tus kheej!
Cim npe nrov: mk256 cas no.: 2271348-04-8, China mk256 cas no.: 2271348-04-8
Xa kev nug
Koj Tseem Yuav Zoo Li
