
Hauj lwm lawm
Chemical Structure: ARV766
CAS Nr.: 2750830-09-0

SIB 766
Catalog No.Qauv: URK-V2520Tsuas yog siv rau Lab.
ARV766 yog ib qho kev xaiv inhibitor ntawm Wnt / beta-catenin signaling pathway, ib txoj hauv kev paub zoo uas ua lub luag haujlwm tseem ceeb hauv kev tswj hwm ntawm cell proliferation, sib txawv, thiab ciaj sia taus.
Kev ua lom lom
ARV766 yog ib qho kev xaiv inhibitor ntawm Wnt / beta-catenin signaling pathway, ib txoj hauv kev paub zoo uas ua lub luag haujlwm tseem ceeb hauv kev tswj hwm ntawm cell proliferation, sib txawv, thiab ciaj sia taus.
ARV766 tau pom tias inhibit qhov kev ua ntawm beta-catenin, ib qho tseem ceeb ntawm Wnt / beta-catenin txoj hauv kev, ua rau kev txo qis ntawm cov phiaj xwm hauv qab uas koom nrog hauv kev loj hlob ntawm tes thiab kev ciaj sia.
Physicochemical Properties
M.Wt |
807.95 |
|
Formula |
C45H54FN7O6 |
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CAS Nr. |
2750830-09-0 |
|
Qhov tshwm sim |
Khoom |
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Cia |
Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos |
Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis |
Solubility |
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Tshuaj npe |
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Cov ntaub ntawv
1. Li, J. et al. (2017). Kev Tshawb Nrhiav thiab Kev Txhim Kho ntawm Me Molecule Modulators ntawm Wnt/beta-Catenin Signaling. Tam sim no tshuaj chemistry, 24(32), 3584–3620.
2. Jang, GB et al. (2015). ARV-825, ARV Adaptable -771 Derivative, Ib txhij Targets AR/BRD4 thiab Vulnerable Cancer Pathways. Cancer cell, 27(4), 678–693.
3. Zhang X., et al. (2018). Antitumor kev ua ntawm ARV-825, BRD4/BET inhibitor, hauv BRG1- cov qog nqaij hlav tsis muaj zog. Cell tuag & kab mob, 9(3), 310.
Cim npe nrov: ARV766 CAS No.: 2750830-09-0, Tuam Tshoj ARV766 CAS No.: 2750830-09-0
Xa kev nug
Koj Tseem Yuav Zoo Li