ARV766 CAS Nr.: 2750830-09-0

ARV766 CAS Nr.: 2750830-09-0

Chemical Structure: ARV766
CAS Nr.: 2750830-09-0

Hauj lwm lawm

Chemical Structure: ARV766

CAS Nr.: 2750830-09-0

product-600-600

 

SIB 766

Catalog No.Qauv: URK-V2520Tsuas yog siv rau Lab.

ARV766 yog ib qho kev xaiv inhibitor ntawm Wnt / beta-catenin signaling pathway, ib txoj hauv kev paub zoo uas ua lub luag haujlwm tseem ceeb hauv kev tswj hwm ntawm cell proliferation, sib txawv, thiab ciaj sia taus.

 

Kev ua lom lom

ARV766 yog ib qho kev xaiv inhibitor ntawm Wnt / beta-catenin signaling pathway, ib txoj hauv kev paub zoo uas ua lub luag haujlwm tseem ceeb hauv kev tswj hwm ntawm cell proliferation, sib txawv, thiab ciaj sia taus.
ARV766 tau pom tias inhibit qhov kev ua ntawm beta-catenin, ib qho tseem ceeb ntawm Wnt / beta-catenin txoj hauv kev, ua rau kev txo qis ntawm cov phiaj xwm hauv qab uas koom nrog hauv kev loj hlob ntawm tes thiab kev ciaj sia.

 

Physicochemical Properties

M.Wt

807.95

Formula

C45H54FN7O6

CAS Nr.

2750830-09-0

Qhov tshwm sim

Khoom

Cia

Hmoov hmoov

-20 degree 3 xyoos;

4 degree 2 xyoos

Hauv Solvent

-80 degree 6 Lub Hlis

-20 degree 1 Lub Hlis

Solubility

 

Tshuaj npe

 

 

Cov ntaub ntawv

1. Li, J. et al. (2017). Kev Tshawb Nrhiav thiab Kev Txhim Kho ntawm Me Molecule Modulators ntawm Wnt/beta-Catenin Signaling. Tam sim no tshuaj chemistry, 24(32), 3584–3620.

2. Jang, GB et al. (2015). ARV-825, ARV Adaptable -771 Derivative, Ib txhij Targets AR/BRD4 thiab Vulnerable Cancer Pathways. Cancer cell, 27(4), 678–693.

3. Zhang X., et al. (2018). Antitumor kev ua ntawm ARV-825, BRD4/BET inhibitor, hauv BRG1- cov qog nqaij hlav tsis muaj zog. Cell tuag & kab mob, 9(3), 310.

 

product-80-80

URK-V2520_COA

product-80-80

URk-V2520_SDS

product-80-80

URK-V2520_TDS

Cim npe nrov: ARV766 CAS No.: 2750830-09-0, Tuam Tshoj ARV766 CAS No.: 2750830-09-0

Koj Tseem Yuav Zoo Li

Hnab khw