Hauj lwm lawm
Chemical Structure: ZT-1a
CAS Nr.: 212135-62-1
ZT-1a
Catalog No.Qauv: URK-V2380Tsuas yog siv rau Lab.
ZT-1a yog ib qho muaj zog thiab xaiv SPAK inhibitor.
Kev ua lom lom
ZT-1a yog ib qho muaj zog thiab xaiv SPAK inhibitor. ZT-1ib qho inhibits NKCC1 thiab txhawb KCCs los ntawm kev txo lawv cov SPAK-dependent phosphorylation. ZT-1a (10 µM) inhibits NKCC1 tab sis txhawb kev ua haujlwm KCC3. Inhibited SPAK-dependent cation-Cl - cotransporters (CCC) phosphorylation hauv vivo.
Physicochemical Properties
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M.Wt |
445.73 |
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Formula |
C22H15Cl3N2O2 |
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CAS Nr. |
212135-62-1 |
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Cia |
Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos |
Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis |
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Solubility |
10 mM hauv DMSO |
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Tshuaj npe |
Benzamide, 5-chloro-N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy- |
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Cov ntaub ntawv
[1]. Jinwei Zhang, et al. Nat Commun. 2020 Peb Hlis 7, 11:78.
URK-V2380_COAURK-V2380_SDSURK-V2380_TDS
Nco tseg: Tag nrho cov khoom ntawm Ureiko tsuas yog siv rau kev tshawb fawb tshawb fawb lossis kev tshaj tawm daim ntawv pov thawj tshuaj, thiab peb tsis muab cov khoom thiab cov kev pabcuam rau kev siv tus kheej!
Cim npe nrov: ZT-1a CAS No.: 212135-62-1, China ZT-1a CAS No.: 212135-62-1
Xa kev nug
Koj Tseem Yuav Zoo Li
