Tsev - Cov khoom - Inhibitors & Agonists - Lwm tus - Paub meej

Mosnodenvir (Synonyms: JNJ-1802) CAS No.: 2043343-94-6

Chemical Structure : Mosnodenvir (Synonyms: JNJ-1802)
CAS Nr.: 2043343-94-6

Xa kev nug

Hauj lwm lawm

Chemical Structure : Mosnodenvir (Synonyms: JNJ-1802)

CAS Nr.: 2043343-94-6

Mosnodenvir (Synonyms: JNJ-1802)

Catalog No.Qauv: URK-V2510Tsuas yog siv rau Lab.

Mosnodenvir inhibits qhov kev ua pov thawj ntawm Nsp14, ua rau muaj kev ua yuam kev hauv RNA ib ntus thiab tiv thaiv tus kab mob los ntawm kev rov ua haujlwm zoo.

Kev ua lom lom

Mosnodenvir inhibits qhov kev ua pov thawj ntawm Nsp14, ua rau muaj kev ua yuam kev hauv RNA ib ntus thiab tiv thaiv tus kab mob los ntawm kev rov ua haujlwm zoo.
Mosnodenvir tsom rau Nsp14 enzyme thiab inhibits proofreading kev ua, tiv thaiv RNA cov kab mob los ntawm replicating zoo.

Physicochemical Properties

M.Wt	582.96
Formula	C₂₆H₂₂ClF₃N₂O₆S
CAS Nr.	2043343-94-6
Qhov tshwm sim	Khoom
Cia	Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos	Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis
Solubility
Tshuaj npe

Cov ntaub ntawv

1. Ivanov KA, Piubelli L, Frers J et al. Ntau yam enzymatic kev ua ub no cuam tshuam nrog mob hnyav ua pa nyuaj ua rau tus mob coronavirus helicase. J Virol. 2004; 78(11):{4}}.

2. Ma Y, Wu L, Shaw N et al. Cov qauv hauv paus thiab kev soj ntsuam ua haujlwm ntawm SARS tus mob coronavirus nsp14-nsp10 complex. Proc Natl Acad Sci USA. 2015; 112(30):9436-9441.

3. Ning X, Luo M. SARS-CoV-2 nucleocapsid protein: a crucial effector for viral replication and host response [published correction appeared in Sci China Life Sci. 2020 Sep; 63(9):1503]. Sci Tuam Tshoj Lub Neej Sci. 2020; 63(10):{10}}. doi: 10.1007/s11427-020-1741-2