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Cabergoline Impurity B CAS No.: 166533-36-4

Chemical Structure: Cabergoline Impurity B
CAS Nr.: 166533-36-4

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Hauj lwm lawm

Chemical Structure: Cabergoline Impurity B

CAS Nr.: 166533-36-4

Cabergoline impurity B

Catalog No.Qauv: URK-V2460Tsuas yog siv rau Lab.

Cabergoline Impurity B yog ib qho tseem ceeb hauv kev tshawb fawb tshuaj, nrog rau kev siv tau zoo hauv kev kho mob ntawm cov hlab ntsha. Nws cov haujlwm muaj zog ua D2 receptor agonist ua rau nws muaj txiaj ntsig zoo rau kev tshawb xyuas cov txheej txheem tom qab cov kab mob no, thiab kev tshawb fawb yav tom ntej hauv cheeb tsam no tau lees paub.

Kev ua lom lom

Cabergoline Impurity B yog ib qho tshuaj lom neeg uas nquag siv hauv kev tshawb fawb tshuaj. Nws yog ib qho derivative ntawm Cabergoline, uas ua raws li agonist ntawm dopamine D2 receptor, ua rau nws muaj txiaj ntsig zoo hauv kev kho tus kab mob Parkinson thiab hyperprolactinemia.
Kev tshawb fawb tau pom tias Cabergoline Impurity B muaj lub zog ua haujlwm raws li D2 receptor agonist, ua rau nws muaj kev cia siab rau kev kawm ntxiv. Nws lub peev xwm los khi rau thiab qhib lub dopamine receptor ua rau nws yog ib qho cuab yeej muaj zog rau kev tshawb xyuas cov txheej txheem tom qab Parkinson tus kab mob thiab lwm yam kev puas hlwb.
Ib txoj kev tshawb nrhiav pom tias Cabergoline Impurity B nthuav qhia kev xaiv siab rau D2 receptor, nrog rau kev ua haujlwm tsawg kawg ntawm lwm yam dopamine receptor subtypes. Qhov kev xaiv no yog qhov xav tau hauv kev tsim tshuaj vim nws txo qis qhov tshwm sim ntawm qhov tsis xav tau.

Physicochemical Properties

M.Wt	451.604
Formula	C26H37N5O2
CAS Nr.	166533-36-4
Qhov tshwm sim	Khoom
Cia	Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos	Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis
Solubility
Tshuaj npe	Cabergoline EP Impurity B

Cov ntaub ntawv

1. Li J., Li Q., Wang J., et al. Synthesis thiab lom tshuaj ntsuam xyuas ntawm cabergoline derivatives li dopaminergic agonists [J]. Molecules, 2017, 22(7): 1126.

2. Chen B, Wang J, Liu Y, et al. Synthesis, characterization thiab dopamine D2 receptor binding kev tshawb fawb ntawm cov tshiab cabergoline derivatives [J]. European Journal of Medicinal Chemistry, 2018, 156: 774-782.

3. Ronca S, Tagliamonte A, Potenza MA, et al. Ib qho tshiab, xaiv heev, tag nrho thiab muaj zog agonist rau dopamine D2 receptor [J]. European phau ntawv journal of medicinal chemistry, 2019, 167: 628-637.