AG120, Ivosidenib CAS No.:1448347-49-6
Chemical Structure: Ivosidenib
CAS Nr.: 1448347-49-6
Hauj lwm lawm
Chemical Structure: Ivosidenib
CAS Nr.: 1448347-49-6
Ivosidenib(AG-120)
Catalog No.Qauv: URK-V690Tsuas yog siv rau Lab.
Ib tug mutant-selective inhibitor ntawm IDH1 (isocitrate dehydrogenase hom 1).
Kev ua lom lom
Ib tug mutant-selective inhibitor ntawm IDH1 (isocitrate dehydrogenase hom 1); sawv cev rau txoj kev muaj txiaj ntsig ntawm kev tshawb nrhiav hauv kev kho mob ntawm IDH1- cov qog hloov pauv.
Ntshav Qab Zib
Phase 3 Clinical
Physicochemical Properties
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M.Wt |
582.961 |
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Formula |
C28H22ClF3N6O3 |
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CAS Nr. |
1448347-49-6 |
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Cia |
Hmoov hmoov -20 degree 3 xyoos; 4 degree 2 xyoos |
Hauv Solvent -80 degree 6 Lub Hlis -20 degree 1 Lub Hlis |
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Solubility |
DMSO: Ntau dua lossis sib npaug li 39 mg / mL |
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Tshuaj npe |
Glycinamide, 1-(4-cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-}chlorophenyl)-N-(3, 3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)-, (2S)- |
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Cov ntaub ntawv
1. Cuyàs E, et al. Oncotarget. 2015 May 20; 6(14):12279-96.
2. Cancer Discov. Peb Hlis 2015; 5(1): 4.
URK-V690_COAURK-V690_SDSURK-V690_TDS
Nco tseg: Tag nrho cov khoom ntawm Ureiko tsuas yog siv rau kev tshawb fawb tshawb fawb lossis kev tshaj tawm daim ntawv pov thawj tshuaj, thiab peb tsis muab cov khoom thiab cov kev pabcuam rau kev siv tus kheej!
Cim npe nrov: ag120, ivosidenib cas no.:1448347-49-6
Xa kev nug
Koj Tseem Yuav Zoo Li
