Txoj kev loj hlob ntawm Ethanone, 1-[1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl]- CAS Nr.: 1173003-55-8
Tso lus
Ethanone, 1-[1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl]- yog ib qho tshiab me me molecule compound uas tau txais kev saib xyuas rau nws cov kev siv tshuaj kho tau zoo. Qhov kev sib xyaw no ua haujlwm los ntawm kev tsom mus rau ib qho receptor tshwj xeeb hauv lub cev hu ua cannabinoid receptor 2 (CB2).
CB2 receptor feem ntau pom muaj nyob rau hauv lub cev tiv thaiv kab mob thiab tau cuam tshuam rau ntau yam kev ua haujlwm ntawm lub cev xws li mob, apoptosis, thiab mob. Yog li ntawd, CB2 receptor tau dhau los ua lub hom phiaj kho kom zoo nkauj rau ntau yam kab mob xws li mob ntev, mob autoimmune, thiab mob qog noj ntshav.
Cov kev tshawb fawb tau pom tias Ethanone, 1-[1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl]- Nws tuaj yeem khi tshwj xeeb rau CB2 receptor, uas ua rau muaj ntau yam cuam tshuam rau lub cev tsis muaj zog. Qee qhov kev tshawb fawb tau pom tias Ethanone, 1-[1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl] - Nws tuaj yeem txo qhov mob thiab txo qis kev loj hlob ntawm cov qog nqaij hlav cancer.
Ntxiv rau cov kev siv tshuaj kho tau zoo no, kev tshawb fawb txog Ethanone, 1-[1-(tetrahydro-2H-pyran-2-yl)-1H-indazol{{ 7}}yl]- tab tom ua tsis tu ncua, thiab nws cia siab tias qhov sib xyaw no yuav muaj kev siv dav dua rau kev kho mob lwm yam kab mob.
Cov ntaub ntawv:
1. Ramer R, Weinzierl U, Schwind B, et al. Cannabinoid receptor 2 signaling nyob rau hauv lub qog tiv thaiv kab mob soj ntsuam thiab qog hlav. J Natl Cancer Inst. 2013; 105(10):800-812.
2. Deng H, Fang Y. Kev Kho Mob Muaj Peev Xwm ntawm Cannabinoids hauv Kev Tiv Thaiv Tshuaj Khomob-induced Adverse Effects: Kev Tshawb Fawb Kev Tshawb Fawb. Pem hauv ntej Pharmacol. Xyoo 2017; 8: 631.
3. Chakravarti B, Ravi J, Ganju RK. Cannabinoids ua cov tshuaj kho mob qog noj ntshav: cov xwm txheej tam sim no thiab kev cuam tshuam yav tom ntej. Oncotarget. 2014; 5(15):{4}}.
